Pineapple Express is a Sativa-dominant Hybrid marijuana strain made by crossing Trainwreck with Hawaiian. Pineapple Express produces long-lasting energetic effects that you can feel right away. The best time to smoke Pineapple Express is in the morning, afternoon, or early evening hours. In terms of flavor, this strain packs a punch to your pallet with bright citrus notes infused with pineapple and earthy pine, thanks to the terpenes of caryophyllene, limonene, and pinene. Medical marijuana patients choose Pineapple Express to relieve symptoms associated with depression, pain, and fatigue.